In what way do you need help? Are you considering moving in with a friend or a partner?
Mine is a student experience, but it still entails sharing my space with people. I lived with 4 guys for three years, and it was fabulous up until the point where i slept with one who i knew liked me. Then in my typically indecisive way, i couldn't agree to a relationship. So the next few months were a mixture of us being the best of friends, then the worst of enemies ... and often communicating by hastily scribbled apologies slipped beneath one another's bedroom doors. When the whole arrangement finally came to an end and he left the country (nothing to do with me, i hasten to add) he cut me out of his life (i was angry, but i understood). However, in the last month or so, he's reignited our friendship, which i'm very pleased about because we were incredibly close.
As for other annoyances involving co-habitation, the only thing that springs to my mind is the washing up. But i firmly believe that guys don't actually see mess, so when the kitchen was strewn with dirty plates and every bit of cutlery encrusted with dried food, i had to bite the bullet, put the marigolds (and some Morrissey) on, and wash up.
I've never regretted living with those guys though; from a female point of view, i'd rather share with guys than girls. All i will say is, never leave a grievance unsaid, just use a bit of tact when saying it ... and if communication does become too difficult, a letter might seem like a cop-out, but in the end, it always cleared the air with us.
I don't think sharing your living quarters is a bad thing at all, it can seem a bit daunting at first, but just use your head when it comes to considering the other person e.g. do they need a bit of space? / what might i have done to upset them? / what can i do or say to cheer them up? Treat them how you would want to be treated and really, nothing can go so wrong that it can't be fixed.
I'm sure you'll be fine.